Ground Glass

Key Facts
  • Nonspecific finding seen in the majority of diffuse lung diseases
  • Often an early sign or less severe sign of diffuse lung diseaseClassically associated with air bronchograms
  • Lung increased opacification but not to the extent of obscuring blood vessels
  • Pathologic correlates nonspecific: normal expiration, interstitial thickening, airspace filling, or partial collapse ie. any interstitial, airsapce or cause of atelectasis
  • Best area of lung to biopsy or serially follow to determine affects of therapy
Pattern
  • Associated findings or nodules, cysts, or septal thickening often helpful in differential
Differential Diagnosis
  • ABC's
  • Alveolar proteinosis
  • ARDS
  • Blood
  • BOOP
  • CMV
  • Contusion
  • Drug toxicity
  • DIP
  • Eosinophilic pneumonia
  • Edema
  • Fibrosis
  • Granulomatous disease
  • Hypersensitivity pneumonitis
References

Collins J, Stern EJ. Ground-glass opacity at CT: The ABCs. AJR 169: 355-367, 1997.