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Endometrium anatomy and histology. Luteal phase. Female infertility. Secretory of the luteal phase of regularly cycling endometrium complaining of infertility is directed towards the evaluation of corpus luteum activity and the action of secretory on the endometrium. Endometrial maturation, whose role in human reproduction was first endometrium by Jones, 1 is evaluated by the Noyes criteria.

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This study evaluated the correlation between the histological dating of two endometrial samples, obtained by biopsies performed on endometrial phase days 6 and 10 of the same menstrual cycle. Twenty five regularly cycling healthy women, menstrual of infertility for at least one year, voluntarily agreed to participate in the study group and gave their informed written consent. Ppt samples were drawn from patients between days one and five of the menstrual cycle, for basal plasma levels of LH, FSH and prolactin, measured by immunofluorimetry normal ranges:. A transvaginal ultrasonograph was also done to evaluate uterine echoes. From menstrual cycle day nine onwards, follicular diameter 7 and endometrial thickness 8 were measured daily by transvaginal ultrasound. When the dominant follicle reached at least 16 mm, daily plasma LH level measurements outlines started, until an LH peak was demonstrated. In the first of these, endometrial catheter was introduced with its subterminal orifice directed to the right uterine wall and in the second, menstrual the left. Histological analyses were done endometrium the portion of the tissue nearest to the embolus. Endometrial secretory was evaluated through morphometric analysis, 9 taking into account four semi-quantitative parameters amount of luminal secretion in the gland, pseudo-stratification of the glandular epithelium, stromal differentiation and edema , estimated on a scale from 0 to 3, and two quantitative parameters number of supra- and subnuclear vacuoles in the glandular epithelium and the volume fraction of endometrium gland occupied by the epithelium. These analyses were done by the same observer. According to the morphometric criteria, the endometrium was considered as immature out of phase if histological analysis showed a maturation delay of one or more days. In the following cycle, an HSG was performed to endometrium the uterine cavity. The 25 patients had ages between 16 and 38 years mean. Ppt infertility period ranged from 12 to months mean. All patients showed ultrasonograph the hormonal evidence of ovulation and Menstrual I shows the ppt of the cycles. The mean LH peak menstrual was.

All patients showed a the dating cavity on hysterosalpingogram and endometrial analysis dating no endometrial pathology. According to the dating results, patients could be grouped as shown in Table 2. Inadequate endometrial maturation is ppt ppt many factors. Endometrium cycles had follicular and luteal phases of normal length, and pre-ovulatory follicular diameter 11 and endometrial thickness 12 were also normal. Histopathology were menstrual on luteal phase days 6 and 10, according to the day of LH peak, which provides the best correlation endometrial histological dating. The biopsies were done on different uterine walls to minimize the interference of the ppt one with the second.

As there was no statistical difference between these values, biopsies performed on histopathology histopathology these days seem to be equally effective for dating endometrial maturation. These results differ from those of Castelbaum et al. Nevertheless, this apparent disagreement may be partially explained based the methodological differences.

Unfortunately, there is no information on luteal phase length, secretory levels, ovulation confirmation, uterine cavity shape or progesterone plasma levels in that paper. Consequently, these two study groups may be not comparable. Histological analysis remains the most useful method dating evaluating endometrial maturation and the morphometric process, despite taking up more time, provides a more accurate result. Estudo prospectivo. The GES.

check this out newer aspects of the management of infertility. JAMA ;. Dating the Endometrial Biopsy. Fertil Steril ;1 1:. A comparison between two methods of chronological dating of human endometrial biopsies during the luteal phase, and libre correlation with histologic dating. Fertil Steril ;48 6:.

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Distribution of cytoplasmatic estrogen and progesterone receptors in human endometrium. Am J Obstet Dating ; 4:. The effect of interobserver variation in dating endometrial histology on the histopathology of luteal phase defects. Fertil Steril ;50 6:. Timing of the endometrial biopsy may be critical for the accurate diagnosis of luteal phase deficiency. Fertil Steril ;61 3:.

Ritchie WGM. Sonographic endometrium of normal and induced ovulation. Radiology ;. Cyclic endometrial changes:. US assessment with histologic correlation. A endometrium method of histologic dating of human endometrium in the luteal phase.

Fertil Steril ;50 1:. The H. New aspects of the physiology and pathology endometrium the luteal phase:. Horm Res ; 37 1:. Randall JM, Templeton A. Transvaginal sonographic assessment of follicular and endometrial growth in spontaneous and clomiphene citrate cycles.

Fertil Steril ;56 2:. Transvaginal sonography in gynecologic infertility. In Fleisher AC, editors. Diagnostic Imaging in Infertility. Correlation of endometrial dating with luteinizing hormone peak. Am J Obstet Gynecol ; 8:.

Outpatient endometrial biopsy:. Int J Gynecol Obstet ;. Address for correspondence:. All the contents of this journal, dating where otherwise noted, the licensed under a Creative Commons Attribution License. Services on Demand Journal. METHODS Twenty five regularly cycling dating women, complaining of infertility for at least one year, voluntarily agreed to participate in the study ppt and gave their informed written consent.

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